1176 Results for "

Citrus hystrix DC.

" in MedChemExpress (MCE) Product Catalog:
Products (1176)

1176 Results for "Citrus hystrix DC." in MCE Product Catalog:

36
Hesperidin
Hesperidin
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36 Publications Verification
Cat. No.: HY-15337
CAS No.: 520-26-3
Purity:  97.15%
Synonyms: Hesperetin 7-rutinoside
Category:  

Flavonoids Anti-aging Flavonones Rutaceae Plants Endogenous metabolite Disease Research Fields Citrus Cancer

Target:  

Apoptosis Autophagy Reactive Oxygen Species (ROS) Endogenous Metabolite

Hesperidin (Hesperetin 7-rutinoside), a flavanone glycoside, is isolated from citrus fruits. Hesperidin has numerous biological properties, such as decreasing inflammatory mediators and exerting significant antioxidant effects. Hesperidin also exhibits antitumor and antiallergic activities .
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30
Hesperetin
Hesperetin
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30 Cited Publications
Cat. No.: HY-N0168
CAS No.: 520-33-2
Category:  

other families Flavonoids Neurological Disease Sunscreen Flavonones Cosmetic Research Plants Disease Research Fields Cancer

Target:  

p38 MAPK Autophagy Apoptosis Reactive Oxygen Species (ROS) NF-κB Bcl-2 Family

Hesperetin is a natural flavanone that can be found in citrus, and acts as a potent and orally active broad-spectrum inhibitor against human UGT activity. Hesperetin induces apoptosis via p38 MAPK activation. Hesperetin displays a range of bioactivities including antioxidant, anti-inflammatory, and anti-cancer. Hesperetin is found to induce cell-cycle arrest at G2/M phase. Hesperetin can reduce Bcl-2 and enhance BaxM. Hesperetin induces apoptosis through inhibiting NF-κB receptor .
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28
Nobiletin
Nobiletin
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28 Cited Publications
Cat. No.: HY-N0155
CAS No.: 478-01-3
Category:  

Flavonoids Neurological Disease Flavones Rutaceae Plants Disease Research Fields Inflammation/Immunology Citrus reticulata Blanco

Target:  

ROR Reactive Oxygen Species (ROS) Apoptosis Autophagy

Nobiletin is a poly-methoxylated flavone from the citrus peel that improves memory loss. Nobiletin is a retinoid acid receptor-related orphan receptors (RORs) agonist. Nobiletin can reduce reactive oxygen species (ROS) levels in differentiated C2C12 myotubes and has anti-inflammation and anti-cancer properties, including anti-angiogenesis, anti-proliferation, anti-metastasis and induced apoptosis .
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27
Calcium disodium edetate hydrate
Calcium disodium edetate hydrate
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27 Cited Publications
Cat. No.: HY-W250119
CAS No.: 23411-34-9
Synonyms: EDTA disodium calcium salt hydrate; Ethylenediaminetetraacetic acid disodium calcium salt hydrate
Calcium disodium edetate hydrate (EDTA disodium calcium salt hydrate) is a metal chelator and antifungal agent. Calcium disodium edetate hydrate chelates Mn 2+, damages mitochondria, and interferes with carbohydrate metabolic pathways, particularly the synthesis of pyruvate in glycolysis. Calcium disodium edetate hydrate inhibits Penicillium digitatum and delays conidial germination. Calcium disodium edetate (hydrate) enhances the host defense system of citrus fruits. Calcium disodium edetate hydrate is applicable to research related to citrus green mold .
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27
Naringin
Naringin
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27 Cited Publications
Cat. No.: HY-N0153
CAS No.: 10236-47-2
Synonyms: Naringoside
Category:  

Citrus × aurantium Linnaeus Flavonoids Leguminosae Flavonones Rutaceae Plants Endogenous metabolite Disease Research Fields Glycyrrhiza uralensis Fisch. Cancer

Target:  

Cytochrome P450 Autophagy Mitophagy Endogenous Metabolite

Naringin is a major flavanone glycoside obtained from tomatoes, grapefruits, and many other citrus fruits. Naringin exhibits biological properties such as antioxidant, anti-inflammatory, and antiapoptotic activities. Naringin also inhibits proliferation and invasion and induces apoptosis in human osteosarcoma cells by inhibiting zinc finger E-box binding homeobox 1 (Zeb1) .
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27
Naringin (Standard)
Naringin (Standard)
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27 Cited Publications
Cat. No.: HY-N0153R
CAS No.: 10236-47-2
Synonyms: Naringoside (Standard)
Category:  

Citrus × aurantium Linnaeus Rutaceae Plants Endogenous metabolite Flavonoids Leguminosae Flavonones Disease Research Fields Glycyrrhiza uralensis Fisch. Cancer

Target:  

Endogenous Metabolite Cytochrome P450 Mitophagy Autophagy Reference Standards

Naringin is a major flavanone glycoside obtained from tomatoes, grapefruits, and many other citrus fruits. Naringin exhibits biological properties such as antioxidant, anti-inflammatory, and antiapoptotic activities. Naringin also inhibits proliferation and invasion and induces apoptosis in human osteosarcoma cells by inhibiting zinc finger E-box binding homeobox 1 (Zeb1) .
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25
Naringenin
Naringenin
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25 Cited Publications
Cat. No.: HY-N0100
CAS No.: 480-41-1
Category:  

Rutaceae Plants Endogenous metabolite Citrus reticulata Blanco Infection Human Gut Microbiota Metabolites Flavonoids Leguminosae Flavonones Phenols Polyphenols Disease Research Fields Glycyrrhiza uralensis Fisch. Inflammation/Immunology

Target:  

Dengue Virus PPAR Reactive Oxygen Species (ROS) Influenza Virus Endogenous Metabolite

Naringenin is the predominant flavanone in Citrus reticulata Blanco; displays strong anti-inflammatory and antioxidant activities. Naringenin has anti-dengue virus (DENV) activity.
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21
Diosmin
Diosmin
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21 Cited Publications
Cat. No.: HY-N0178
CAS No.: 520-27-4
Category:  

Cardiovascular Disease Flavonoids Flavones Rutaceae Plants Disease Research Fields Citrus

Target:  

Aryl Hydrocarbon Receptor

Diosmin is a flavonoid found in a variety of citrus fruits and also an agonist of the aryl hydrocarbon receptor (AhR).
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19
SGI-1027
SGI-1027
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19 Cited Publications
Cat. No.: HY-13962
CAS No.: 1020149-73-8
Purity:  99.77%
Target:  

DNA Methyltransferase Apoptosis

Research Areas:  

Cancer

SGI-1027 is a DNA methyltransferase (DNMT) inhibitor, with IC50s of 7.5 μM, 8 μM, and 12.5 μM for DNMT3B, DNMT3A, and DNMT1 with poly(dI-dC) as substrate.
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16
Tangeretin
Tangeretin
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16 Cited Publications
Cat. No.: HY-N0133
CAS No.: 481-53-8
Synonyms: Tangeritin; NSC53909; NSC618905
Category:  

other families Flavonoids Flavones Plants Disease Research Fields Cancer

Target:  

Notch Apoptosis

Tangeretin (Tangeritin), a flavonoid from citrus fruit peels, has been proven to play an important role in anti-inflammatory responses and neuroprotective effects in several disease models, and is a Notch-1 inhibitor.
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14
Sodium citrate dihydrate
Sodium citrate dihydrate
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14 Cited Publications
Cat. No.: HY-B1610
CAS No.: 6132-04-3
Synonyms: Trisodium citrate dihydrate; Citric acid trisodium salt dihydrate
Category:  

Cardiovascular Disease Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields

Target:  

Environmental Pollutants Endogenous Metabolite Apoptosis Bacterial

Sodium citrate dehydrate (Trisodium citrate dihydrate) is a natural product with oral activity that can be found in citrus fruits. Sodium citrate dehydrate can inhibit the proliferation of tumor cells and induce apoptosis. Sodium citrate dehydrate has antibacterial, anti-tumor and antioxidant activities. Sodium citrate dehydrate can be prepared as a cosolvent or buffer .
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12
Phen-DC3 Trifluoromethanesulfonate
Phen-DC3 Trifluoromethanesulfonate
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12 Cited Publications
Cat. No.: HY-15594A
CAS No.: 929895-45-4
Purity:  98.99%
Synonyms: Phen-DC3 Triflate
Target:  

G-quadruplex

Research Areas:  

Cancer

Phen-DC3 Trifluoromethanesulfonate is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases with IC50s of 65±6 and 50±10 nM, respectively.
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11
ACBI1
ACBI1
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11 Cited Publications
Cat. No.: HY-128359
CAS No.: 2375564-55-7
Purity:  99.92%
Target:  

PROTACs SWI/SNF Complex Apoptosis

Research Areas:  

Cancer

ACBI1 is a potent and cooperative SMARCA2, SMARCA4 and PBRM1 degrader with DC50s of 6, 11 and 32 nM, respectively. ACBI1 is a PROTAC degrader. ACBI1 shows anti-proliferative activity. ACBI1 induces apoptosis .
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11
Ligustrazine hydrochloride
Ligustrazine hydrochloride
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11 Cited Publications
Cat. No.: HY-N0935
CAS No.: 76494-51-4
Synonyms: Chuanxiongzine hydrochloride; Tetramethylpyrazine hydrochloride
Category:  

Alkaloids Other Alkaloids Other Diseases Dicerothamnus rhinocerotis Plants Umbelliferae Disease Research Fields

Target:  

Reactive Oxygen Species (ROS) Akt NO Synthase Aminotransferases (Transaminases)

Ligustrazine hydrochloride is an orally active, blood-brain barrier-permeable alkaloid. It can be isolated from Ligusticum striatum DC. Ligustrazine hydrochloride reduces ROS, upregulates the levels of p-Akt/Akt and p-eNOS/eNOS, and decreases ALT and AST. It inhibits glutamate excitotoxicity, calcium overload, oxidative stress, ischemia-reperfusion injury and atherosclerotic plaque progression, enhances synaptic plasticity, and improves neurological function, cerebral infarct volume and brain water content. Ligustrazine hydrochloride possesses anti-inflammatory, antioxidant, lipid-lowering, endothelial protective and hepatoprotective activities. It can be used in studies related to ischemic stroke, cerebral ischemia-reperfusion injury and atherosclerosis .
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9
Neohesperidin
Neohesperidin
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9 Cited Publications
Cat. No.: HY-N0101
CAS No.: 13241-33-3
Synonyms: Hesperetin 7-O-neohesperidoside
Category:  

Rutaceae Plants other families Flavonoids Flavonones Phenols Polyphenols Disease Research Fields Inflammation/Immunology Citrus

Target:  

β-catenin Wnt

Neohesperidin is a flavonoid compound abundant in citrus plants with antioxidant and anti-inflammatory effects. Neohesperidin can upregulate the Wnt/β-catenin signaling pathway, enhance the nuclear translocation of β-catenin and the differentiation of bone marrow stromal cells .
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9
LY 345899
LY 345899
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9 Cited Publications
Cat. No.: HY-101943
CAS No.: 10538-99-5
Purity:  ≥98.0%
Target:  

Methylenetetrahydrofolate Dehydrogenase (MTHFD)

Research Areas:  

Cancer

LY 345899 is a Folate analog and is a methylene tetrahydrofolate dehydrogenase (MTHFD1; DC301) and MTHFD2 inbhibitor with IC50 values of 96 nM and 663 nM, respectively and a Ki of 18 nM for MTHFD1 .
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8
PROTAC FAK degrader 1
PROTAC FAK degrader 1
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8 Cited Publications
Cat. No.: HY-119932
CAS No.: 2301916-69-6
Purity:  99.25%
Target:  

PROTACs FAK Akt

Research Areas:  

Cancer

PROTAC FAK degrader 1 (Compound PROTAC-3) is a selective and effective degrader of Fak PROTAC with a DC50 of 3.0 nM. PROTAC FAK degrader 1 reduces the ability of cancer cells to migrate and invade. PROTAC FAK degrader 1 can be used in the study of tumor .
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7
Isosakuranetin
Isosakuranetin
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7 Cited Publications
Cat. No.: HY-N2131
CAS No.: 480-43-3
Category:  

Flavonoids Flavanols Other Diseases Rutaceae Plants Disease Research Fields Citrus bergamia

Target:  

TRP Channel

Isosakuranetin is a flavanone flavonoid which can be found in the fruit of Citrus bergamia. Isosakuranetin is a TRPM3 blocker .
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7
Narirutin
Narirutin
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7 Cited Publications
Cat. No.: HY-N0804
CAS No.: 14259-46-2
Category:  

Flavonoids Flavonones Rutaceae Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology Citrus

Target:  

Bacterial

Narirutin, one of the active constituents isolated from citrus fruits, has antioxidant and anti-inflammatory activities. Narirutin is a shikimate kinase inhibitor with anti-tubercular potency .
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7
Sodium methylparaben, 99%
Sodium methylparaben, 99%
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7 Cited Publications
Cat. No.: HY-W016806
CAS No.: 5026-62-0
Synonyms: Sodium methyl 4-hydroxybenzoate, 99%
Sodium methylparaben, 99% (Sodium methyl 4-hydroxybenzoate, 99%) is an antifungal agent .
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